Maduramicin in poultry feed

Maduramicin in poultry feed

Maduramicin in poultry feed. Maduramicin is an ionophoric polyether antibiotic that is commonly used as a coccidiostat in poultry and livestock feed. It is primarily used to control coccidiosis, a parasitic disease caused by protozoa of the genus Eimeria.

Coccidiosis can affect the digestive and intestinal tracts of animals, leading to reduced growth, poor feed conversion, and sometimes mortality.

Maduramicin acts by disrupting the ion balance across cell membranes in the coccidia, affecting their ability to replicate and causing their death.

Coccidiosis in poultry

Coccidiosis is a common and economically significant parasitic disease affecting poultry, caused by protozoa of the genus Eimeria. These microscopic parasites invade the intestinal lining of birds, leading to various degrees of intestinal damage and associated clinical symptoms.

Coccidiosis is prevalent in poultry farms worldwide and poses a significant challenge to the poultry industry.

Maduramicin in poultry feed

Coccidiostats are substances that control the growth of the protozoan parasites of the genus Eimeria, which cause coccidiosis in poultry.

Coccidiosis is a parasitic disease affecting the digestive and intestinal tracts of poultry, leading to reduced growth, poor feed conversion, and, in severe cases, mortality.

Mode of Action

Maduramicin acts as an ionophore, disrupting the ion balance across cell membranes in the coccidia. This interference affects the ability of the parasites to replicate, ultimately leading to their death.

Effective Against Various Eimeria Species

Maduramicin is effective against several species of Eimeria that commonly infect poultry, including E. tenella, E. maxima, and E. acervulina.

Dosage and Administration

The use of Maduramicin in poultry feed is regulated, and it’s essential to follow recommended dosage guidelines provided by regulatory authorities and veterinarians. It is commonly incorporated into poultry feed to ensure birds receive the appropriate concentration for coccidiosis control.

Prevention and Control

Maduramicin is used as a preventive measure to control coccidiosis in poultry. It helps reduce the impact of the disease on growth rates, feed efficiency, and overall flock health.


While Maduramicin and other coccidiostats are valuable tools in controlling coccidiosis, it’s important to use them judiciously and in accordance with recommended guidelines.

Continuous use of the same coccidiostat without rotation can lead to the development of resistance in coccidia populations, reducing the efficacy of the treatment.


  1. Cygro 1% 20 kg (Alpharma)
  2. Maduramycin Ammonium 1% Premix (Promois)
  3. Zamax 25 kg (Zamira) Australia.
  4. Medicox


In conclusion, Maduramicin, an ionophoric polyether antibiotic, plays a crucial role in the poultry and livestock industry as a coccidiostat.

Its effectiveness against various Eimeria species, the causative agents of coccidiosis, makes it a valuable tool in preventing and controlling this parasitic disease.

By disrupting ion balance across cell membranes, Maduramicin impedes the replication of coccidia, contributing to improved flock health and productivity.


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